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Steady-State Approximation

Assumes that the rate of formation of a product equals its rate of consumption, simplifying kinetic analysis within metabolic pathways.

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The statement of the theorem

For an intermediate species

I

in a metabolic pathway, the Steady-State Approximation (SSA) dictates that the net rate of change of its concentration is zero:\n

\frac{d[I]}{dt} = 0

\nThis implies that the rate of formation of

I

equals the rate of consumption of

I

at steady state.