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Starling's Law of the Heart

States that the force of contraction (stroke volume) is proportional to the degree of ventricular stretch (end-diastolic volume). It is a fundamental determinant of cardiac output.

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The statement of the theorem

The stroke volume

SV

is functionally dependent on the end-diastolic volume

EDV

via a proportionality relationship, assuming constant afterload:

SV \propto EDV