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Spindle Assembly Checkpoint (SAC)

A surveillance mechanism that prevents the premature entry of chromosomes into mitosis until all chromosomes are properly attached to the spindle microtubules.
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The statement of the theorem

Let SS be the state of the cell cycle, where S→AnaphaseS \to \text{Anaphase} is the transition of interest. Define the attachment status function A:K→{0,1}\mathcal{A}: K \to \{0, 1\}, where KK is the set of kinetochores, and A(k)=1\mathcal{A}(k) = 1 if kinetochore kk is properly attached to a spindle microtubule, and A(k)=0\mathcal{A}(k) = 0 otherwise. The Spindle Assembly Checkpoint (SAC) enforces the condition that the transition S→AnaphaseS \to \text{Anaphase} is only permitted if the global attachment satisfaction function Φ\Phi is true:\nΦ=∏k∈KA(k)=1\Phi = \prod_{k \in K} \mathcal{A}(k) = 1
Source: Wikipedia